Common question and answer about PRP treatment at Revival Clinic 

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What is PRP ? 

PRP or platelet rich plasma is the treatment which use your own blood, spin it in the centrifuge, take the platelet rich part and re- inject it back to  your body any where that you want to repair or rejuvenate  

You may heard about many term of this treatment such as PRP, PRF , Vampire facial, vampire facelift, PPP next I will explain you all about the different of these term and how to use it  

First I would Like to start with the history of PRP which will give you more idea about how safe of this treatment and the variety of use 

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The history of PRP 

In 1970s haematologist  started the concept and description of the PRP which mean the plasma with higher concentration of platelet count , this PRP use For  transfusion  to treat patients with Low platelet count. 

Ten years later, PRP started to be used in face and neck surgery as PRF. F is short for fibrin. This  fibrin had the potential to assist the wound healing , anti-inflammatory  and stimulated new cell production . 

Later on PRP extensively used in many field such as sport injury , cardiac surgery to reduce the sternal wound complication , in gynecology also to facilitate the wound healing , in urology for erectile dysfunction   and also in plastic surgery, ophthalmology. Or basically  any where that you have the wound to heal, PRP can be benefit, since the natural function of platelet, is to assist the healing and regeneration. 

In dermatology field, prp also has wide variety use such as tissue regeneration, wound healing, scar treatment, skin rejuvenation or anti-aging for skin and also for hair loss 

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PRP, mechanism of action ? 

Imagine if you have got a knife cut on your finger, then  the bleeding starts, at this step your platelet will do it’s job for wound healing by releasing various type of Growth factor . such as platelet derived growth factor or PDGF which stimulate new stem cell and collagen production, these growth factor also have anti-inflammatory properties to reduce the inflammation and, assist the healing process

 

 

PRF,PRFM,PRP,PPP what’s the different ? 

To make this easier for understanding, I will draw the diagram,  how to prepare all this blood products  

Start with the whole blood 

If we added anti-coagulant such as ACD and then double spin with the centrifuge what we get is red blood cell on the bottom , in the middle or we called Buffy coats layer this is PRP or platelet rich plasma and on the uppermost layer is the plasma with small amount of platelet so we call PPP or platelet poor plasma  

So by this way, what we get is PRP and PPP 

In the other way if we prepare the blood without adding any anti-coagulant with the right spinning setting and right duration of spin, we will get platelet rich fibrin ,this clumping form can’t inject with needle, so mainly use to fill the whole in the bone or for the  teeth surgery. 

Again without anti-coagulant with the right setting we also can get  PRFM or platelet rich fibrin matrix, which is able to inject with the needle, so we can use this for skin rejuvenation and for hair-loss treatment. 

 

 

PRF,PRFM,PRP,PPP what’s is the best ? Which type I use for myself ?

Platelet rich plasma is the first generation, that we use ourself blood for the regenerative medicine 

Platelet-rich fibrin matrix (PRFM) or PRF, is an enhanced version of PRP, which  believed to have superior quality, in helping wound healing.

According to the research from Annals of medicine and surgery , publish on June 2021,  comparing the healing ability of PRP and pRFM on the skin graft, they found that , PRFM improving and accelerating the process of wound healing , better than PRP , due to the higher number of white blood cell and fibroblast.

Based on the research comparative study of platelet count, from Department of Haematology, Royal Hallamshire Hospital in  UK, they  found that PRF has higher number of platelet count than PRP, as show on this table 

Myself personally I choose PRFM since it less painful and it pure natural from my own blood. 

 

 

How about PPP ? Is it just the waste product ? 

In platelet poor plasma, even it has small amount of platelet but also has fibrinogen and growth factor, according to the research publish in 2013 on tissue engineering journal, found that The fibrin network of PPP can help bone regeneration in animal study. 

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How about Platelet activation steps ? Is it necessary ? 

You may heard about platelet activation step, by  using calcium chloride or thrombin 

Some doctor activate platelets by this method first , while others just apply platelets without activating them, which way is better ? 

Recent studies found that the activation  is not necessary because, at the time of administration, the platelets are automatically released and ready to do their function.

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Prepare yourself for PRP treatment. 

To make your blood the best quality,  please avoid oily food ,the meal before treatment, because oily food will digest and absorb, to become the part of your plasma. Eating a healthy meal for your better plasma quality. 

Some may suggest fasting before the treatment, I wouldn’t recommend for the first session, fasting with multiple needle injection treatment  can make you feel fainting for people who sensitive with fasting or needle. 

If you have beard, and you would like to do the treatment, on the skin under the beard area, you better shave your beard  in the morning on your treatment day 

PRP injection for hair , please shampoo your hair in the morning on the treatment day 

 

 

Vampire facial , PRP treatment for face how we do it at Revival Clinic ?

After you choose what type of PRP, you would like to go on , between PRP of PRFM , then the treatment steps  is 

1. first we Deep clean your face remove the your make up from your skin 

2. Then Apply numbness cream for about 30 to 40 minutes 

3. and draw your blood to prepare PRP or PRFM  preparation for 

        Generally 10 ml of whole blood will get about 1 ml of PRP we use about 40 to 50 ml in each session 

        Incase that we like to add more volume you can request to use PPP too there is no additional charge 

        For PRFM we get about one third of volume of your whole blood we take 

1. After clean numbness clean from your face next step is the injection 

2. My injection plan  is 

   1. Inject deep into the volume loss area the to prevent the further volume loss and to stimulate new collagen production 

   2. Inject in the dermis to improve skin quality if you can accept the chance of bruising which will resolve by itself we also can inject around the eyes to improve skin texture and colour 

   3. Apply with micro needling to rejuvenate the upper most skin layer 

Basically we treat all skin layer from the deep , middle and super facial 

My style is to tailor made your treatment to be the best for you, So I would like to hear and discuss about what is your concern, what area is your priority 

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Vampire facial how often should I do the treatment ? 

 Generally for the initial phrase I would recommend once a month for 3 to 4 times then after that we call it the maintenance phrase it could be once every 4 to 6 month depend on your health and lifestyle. 

Dont’ worried if your can’t follow all these schedule , this treatment still benefit for your skin anyway. 

Our ageing process never stop so the maintenance phrase is to combat with your natural ageing process of skin. 

If your work hard play hard expose to the sun a lot you may need multiple time a year for the maintenance phrase, If you avoid strong sun light eat healthy food keep sugar with the minimum , your skin ageing will go slower and we don’t need frequent treatment

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Vampire facial aftercare guide 

The day after treatment avoid exercise, better rest in the clean environment for the first day if you feel uncomfortable you can rinse your face with cold bottle of water 

I recommend to keep all your routine skin care in the fridge and switch to sensitive skincare product for the first week 

After care in details are importation to prevent complication and to reach the most benefit from the treatment 

The rule is as long as you still your skin red it mean you need a special care for your skin … use sensitive skin care product and avoid strong sunlight 

Never too much for the moisturiser for the first week , apply moisture keep your skin hydrate this will assist the skin healing and new collagen production 

Make sure that you get enough nutrition especially protein and vitamin C , you can’t produce new collagen without it .

For all treatment that we aim for new collagen production your health status is the factor for the good result , smoking , sun damage , malnutrition these factor interfere the optimal result .

 

 

PRP for hair 

PRP injection to scalp is widely use to treat hairless problem

It’s safe and effective ,can be used and single treatment or adjunct with oral and topical treatment for hairless

Prepare yourself for the treatment please shampoo your hair the morning before come for the treatment 

After we get PRP or PRFM we will inject to the scalp, first priority is the area which has hair thinning and next inject to area which may have hair loss in the future. This treatment can be both treatment and prevention .

We can use numbness cream , lidocaine injection or ice compression to reduce the uncomfortable during the injection 

Treatment in details I prefer to  tailor made design depend on hair style scalp condition and hair-loss problem 

After care , the day after treatment we prefer you to rest in the clean environment , avoid vigorous sport which cause sweating to prevent infection or inflammation , After treatment we will clean your scalp so no need to shampoo the evening after treatment 

Tomorrow you can resume normal daily life, shouldn’t pick or scratch any scalp on the needle mark. 

The first result that you will see is your hairless will be reduce as soon as in the first month 

For the new hair grow it take months to starts you will see the maximum effect after start regular treatment for 1 year 

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Is there any where else we can use blood for rejuvenation ? 

Basically you can use PR  for everywhere , what we have dones here is face , neck , scalp , hand and scar 

 

 

PRP, PRFM package and Price at Revival Clinic 

For all technique that we discuss the single treatment is 10,000 THB per treatment 

or 4 times package for 34,000 THB There is no extra charge 

and for the package treatment you will get 1 set of after care skin care product for free

 

 

Is there any possible side effect ? 

Bruising is possible complication especially people who take supplement such as fish oil , gingko My technique to minimum chance for bruising is to pay attention in detail nothing take a closure look to avoid visible blood vessel and stop bleeding immediately after the bleeding to prevent the big bruise . Anyway bleeding will resold by itself in 1 to 2 week depend on the size. Around the eyes is the area the easy to bruise if you would like to inject around the eyes especial over your eye bag there is like 50-50% chance to have small bruise follow the needle mark

Feeling tight or headache is depend on the volume we inject especially temporal area but will resolve in 24 hrs 

trigger inflame  Acne : for people who still have active acne I recommend to use PRP with fractional laser instead of micro needling to reduce the chance of triggering acne . You can choose to switch between fractional laser or micro needling there is no extra charge . 

PRP is safe and effective treatment. You may heard about other serious side effect but that come because they mix pop with something else such as dermal filler or other material . Not only pure PRP. 

Sterile technique is also vital. All kind of needle have to throw away using only for one person. Reuse needle can spread blood born diseases and increase risk of infection.