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“Invest in your hair it is the crown you never take off”

Mesotherapy is a non-invasive and non-surgical cosmetic hair restoration procedure.
Superficial microinjections are inserted just below the epidermal layer of the skin into the appropriate tissues to stimulate the mesoderm layer in the skin, which lies at a depth of about 1mm beneath the surface, in order encourage the hair’s natural regeneration and proliferation process.
Mesotherapy treatment has now been used for decades to successfully restore luster and volume to thinning hair and to promote significant hair regrowth for both women and men who have experienced the hair loss.

For hair restoration treatments, the Mesotherapy solution injected into the scalp contains a special combination of placenta extract.
The treatment restores hormone balance at a gradual pace, which enables the steady growth of new, healthy hair strands.


Effectiveness of Mesotherapy for Hair Restoration

Mesotherapy has been shown to be just as effective and sometimes more effective than oral tablets for hair restoration and rejuvenation. Learn more about restoring the hairline in particular .
Orally administered treatments must first pass through the gastrointestinal tract and be metabolized by the liver before they are released into the bloodstream.
This digestive process significantly reduces the amount of medication that reaches the affected area.
In contrast, Mesotherapy is able to deliver a much smaller dose of treatment direct to the affected area; in the case of hair loss, the hair follicle; where it is directly required and can be immediately assimilated.
Mesotherapy has been shown in a clinical trial to be more effective than topical application of Minoxidil for successful hair restoration treatment in females suffering from hair loss.

" Overall, our findings suggest that HPE promotes hair growth and may thus provide the basis of a novel therapeutic strategy for the clinical treatment of hair loss."

Major Nutrients in the Placenta Extract

Major Nutrients in the Placenta

• Amino acids such as leucine, lysine, valine, threonine, isoleucine, glycine, alanine, and arginine.
• Active peptides :key to pharmacological activity.
• Proteins such as albumin, and globulin.
• Mucopolysaccharides such as hyaluronic acid, and chondroitin.
• Vitamins such as vitamin B1, B2, B6, B12, C, D, E, and niacin.
• Minerals such as calcium, sodium, potassium, phosphorus, magnesium, zinc, and iron.
• Nucleic Acids such as DNA, RNA, and metabolic products.
• Enzymes: Close to 100 varieties have been found including alkaline phosphatise acid phosphatise.

Human Placenta Extract : Hair growth promotion

Alopecia is a constantly increasing problem attributable to hormones, genetic factors, autoimmune diseases, medications and stress which alter the hair follicle cycle and causes hair loss. Previous report by Seo et al. showed the effectiveness of placental extracts in hair growth promotion. The hair growth of depilated C57BL/6 mice was investigated by applying human placental extracts topically once a day for fifteen days consecutively. Gross examination and histological analysis showed the placental extracts marked increased hair regrowth and also increased the expression of FGF-7, which play pivotal roles in maintain the anagen phase and the cellular proliferation of hair follicles suggesting that it may be a good candidate for the treatment of alopecia.

This quality of placental extracts allows its successful application in treatment of hair loss. European Wellness Centers International Group has employed mesotherapy with MF+ Placental extracts in the scalp area as a part of the therapies that promote hair growth in male individuals.

Human placental extract exerts hair growth-promoting effects

Human placental extract (HPE) is widely used in Korea to relieve fatigue. However, its effects on human dermal papilla cells (hDPCs) remain unknown. In the present study, in an effort to develop novel therapies to promote hair growth, we screened HPE. We demonstrate that HPE has hair growth‑promoting activities and induces β‑catenin expression through the inhibition of glycogen synthase kinase‑3β (GSK‑3β) by phosphorylation in hDPCs. Treatment with HPE significantly increased the viability of the hDPCs in a concentration‑dependent manner, as shown by bromodeoxyuridine (BrdU) assay. HPE also significantly increased the alkaline phosphatase (ALP) expression levels. The increased β‑catenin levels and the inhibition of GSK‑3β (Ser9) by phosphorylation suggested that HPE promoted the hair-inductive capacity of hDPCs. We compared the effects of treatment with HPE alone and treatment with HPE in conjunction with minoxidil (MXD). We found that HPE plus MXD effectively inhibited GSK‑3β by phosphorylation (Ser9) in the hDPCs. Moreover, we demonstrated that HPE was effective in inducing root hair elongation in rat vibrissa hair follicles, and that treatment with HPE led to a delay in catagen progression. Overall, our findings suggest that HPE promotes hair growth and may thus provide the basis of a novel therapeutic strategy for the clinical treatment of hair loss.

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